Examples in practise - Chilling
AVECIA Limited, in Huddersfield, UK, is one of the leading producers of pharmaceutical ingredients (API = Active Pharmaceutical Ingredients). They placed an order with LAUDA to controll a highly sensitive low-temperature process stage for the synthesis of a product for the treatment of the ophthalmic disease, Glaucoma. The problem was to control the very exothermic reaction at a temperature level of -80 °C. In order to meet the requirements of high reliability and low operating costs, LAUDA and AVECIA chose a process cooling unit. An electric heater of 36 kW had to be installed in the unit in order to meet the requested heating cycle. The unit had to be independent from central energy systems and installed outside in a hazardous area (Zone 1/T4). This ecentralised concept increased the customer’s flexibility to move the unit to a different place – if required – in order to react to changed market conditions.
On the right is a list of application examples in practice. To see the pictures click on the text.
High purity by chilling
Application:
Heating/chilling of a reactor in a temperature range from -80 up to 140 °C; outside installation in hazardous area.
- Heating
The was independent from the customer’s steam system; heating was
generated by means of an electric heater.
- Chilling
It was decided not to use liquid nitrogen; chilling was generated by using
a process cooling unit (twocircuit cascade).
- Air- or water-cooled refrigeration module
Due to the fact that cooling water was not used, an air-cooled lamella
condenser with fans was mounted on the top of the unit.
LAUDA modular solution: Process cooling unit Type SUK 400 L II Ex
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